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X. Edward Guo
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Proceedings Papers

A Generalized Self-Consistent Method for Osteonal Cortical Bone Modeling

X. Edward Guo, X. Neil Dong, Y. Young Huang
Proc. ASME. IMECE98, Advances in Bioengineering, 271-272, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0135
https://doi.org/10.1115/IMECE1998-0135
View Paper titled, A Generalized Self-Consistent Method for Osteonal Cortical Bone Modeling
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Topics: Bone, Modeling, Composite materials, Fibers, Damage mechanics, Mechanical properties, Microcracks, Bone mechanics, Elasticity, Fracture mechanics
Proceedings Papers

An Improved In Vivo Rat Tail Vertebra Model for the Study of Trabecular Bone Adaptation

Mark J. Eichler, Chi Hyun Kim, X. Edward Guo
Proc. ASME. IMECE99, Advances in Bioengineering, 167-168, November 14–19, 1999
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1999-0430
https://doi.org/10.1115/IMECE1999-0430
View Paper titled, An Improved In Vivo Rat Tail Vertebra Model for the Study of Trabecular Bone Adaptation
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Topics: Bone, Magnetic resonance imaging, Stress, Bone fractures, Computerized tomography, Finite element analysis, Modeling, Surgery
Proceedings Papers

Transversely Isotropic Model of Osteonal Cortical Bone: Contribution of Haversian and Resorptive Porosity

X. Neil Dong, Y. Young Huang, X. Edward Guo
Proc. ASME. IMECE99, Advances in Bioengineering, 183-184, November 14–19, 1999
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1999-0438
https://doi.org/10.1115/IMECE1999-0438
View Paper titled, Transversely Isotropic Model of Osteonal Cortical Bone: Contribution of Haversian and Resorptive Porosity
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Topics: Bone, Porosity, Canals, Cavities
Proceedings Papers

The Influence of Experiment Conditions on Osteon Pushout Tests

X. Neil Dong, X. Edward Guo
Proc. ASME. IMECE2001, Advances in Bioengineering, 63-64, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/BED-23031
https://doi.org/10.1115/IMECE2001/BED-23031
View Paper titled, The Influence of Experiment Conditions on Osteon Pushout Tests
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Topics: Bone, Cements (Adhesives)
Proceedings Papers

Predicting a Power Law Between Elastic Modulus and Porosity in Cortical Bone: A Micromechanics Model

X. Neil Dong, X. Edward Guo
Proc. ASME. IMECE2001, Advances in Bioengineering, 65-66, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/BED-23032
https://doi.org/10.1115/IMECE2001/BED-23032
View Paper titled, Predicting a Power Law Between Elastic Modulus and Porosity in Cortical Bone: A Micromechanics Model
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Topics: Bone, Elastic moduli, Micromechanics (Engineering), Porosity, Canals, Shells, Stress
Proceedings Papers

An Exploration of Cell Stress and Deformation Under Shear Flow

X. Edward Guo, Erica Takai, Kai Liu, Xiaodong Wang
Proc. ASME. IMECE2001, Advances in Bioengineering, 321-322, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/BED-23160
https://doi.org/10.1115/IMECE2001/BED-23160
View Paper titled, An Exploration of Cell Stress and Deformation Under Shear Flow
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Topics: Deformation, Shear flow, Stress, Flow (Dynamics), Bone, Shear stress, Fluids, Osteoblasts, Signals, Arthroplasty
Proceedings Papers

Impact of Thresholding Techniques on Micro-CT Image Based Computational Models of Trabecular Bone

Mark J. Eichler, Chi Hyun Kim, Ralph Müller, X. Edward Guo
Proc. ASME. IMECE2000, Advances in Bioengineering, 215-216, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2588
https://doi.org/10.1115/IMECE2000-2588
View Paper titled, Impact of Thresholding Techniques on Micro-CT Image Based Computational Models of Trabecular Bone
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Topics: Bone, Computer simulation, Mechanical properties, Bone fractures, Finite element analysis, Fracture (Materials), Fracture (Process)
Journal Articles

Regional Variations of HR-pQCT Morphological and Biomechanical Measurements of Bone Segments and Their Associations With Whole Distal Radius and Tibia Mechanical Properties

Bin Zhou, Zhendong Zhang, Yizhong Jenny Hu, Ji Wang, Y. Eric Yu, Shashank Nawathe, Kyle K. Nishiyama, Tony M. Keaveny, Elizabeth Shane, X. Edward Guo
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2019, 141(9): 091008.
Paper No: BIO-19-1087
https://doi.org/10.1115/1.4044175
Published Online: August 2, 2019
View Article titled, Regional Variations of HR-pQCT Morphological and Biomechanical Measurements of Bone Segments and Their Associations With Whole Distal Radius and Tibia Mechanical Properties
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Topics: Bone, Resolution (Optics), Stiffness, Computerized tomography, Biomechanics, Finite element analysis, Mechanical testing, Mechanical properties
Journal Articles

Special Issue: A Tribute to Dr. Y. C. Fung

Hai-Chao Han, Shu Qian Liu, X. Edward Guo
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Guest Editorial
J Biomech Eng. September 2019, 141(9): 090301.
Paper No: BIO-19-1311
https://doi.org/10.1115/1.4044065
Published Online: July 10, 2019
View Article titled, Special Issue: A Tribute to Dr. Y. C. Fung
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Topics: Bioengineering, Biomechanical engineering, Biomechanics, Biomedicine, Students, Biological tissues, Engineering teachers, Biomedical engineering, Biotransport, Blood
Journal Articles

Accurate and Efficient Plate and Rod Microfinite Element Models for Whole Bone Segments Based on High-Resolution Peripheral Computed Tomography

Ji Wang, Bin Zhou, Yizhong Jenny Hu, Zhendong Zhang, Y. Eric Yu, Shashank Nawathe, Kyle K. Nishiyama, Tony M. Keaveny, Elizabeth Shane, X. Edward Guo
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2019, 141(4): 041005.
Paper No: BIO-17-1568
https://doi.org/10.1115/1.4042680
Published Online: February 25, 2019
View Article titled, Accurate and Efficient Plate and Rod Microfinite Element Models for Whole Bone Segments Based on High-Resolution Peripheral Computed Tomography
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Topics: Bone, Stiffness, Yield strength, Mechanical testing, Resolution (Optics), Spinal fractures, Computation
Proceedings Papers

Geometric Control of Mechanical Forces and Stem Cell Differentiation

Leo Q. Wan, Sylvia M. Kang, George Eng, X. Lux Lu, B. Bob Huo, Jeffrey Gimble, X. Edward Guo, Van C. Mow, Gordana Vunjak-Novakovic
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 55-56, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192680
https://doi.org/10.1115/SBC2008-192680
View Paper titled, Geometric Control of Mechanical Forces and Stem Cell Differentiation
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Topics: Biological tissues, Biology, Feedback, Stem cells
Proceedings Papers

In Situ Transient Deformation of Chondrocytes Under Unconfined Compression: Experimental Measurements and Triphasic Finite Element Model

Morakot Likhitpanichkul, X. Edward Guo, Van C. Mow
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 261-262, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176105
https://doi.org/10.1115/SBC2007-176105
View Paper titled, In Situ Transient Deformation of Chondrocytes Under Unconfined Compression: Experimental Measurements and Triphasic Finite Element Model
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Topics: Chondrocytes, Compression, Deformation, Finite element model, Transients (Dynamics), Cartilage, Finite element analysis, Physiology, Signals, Stress
Proceedings Papers

Contributions of Trabecular Rods of Various Orientations in Determining the Elastic Properties of Human Vertebral Trabecular Bone

Xiaowei S. Liu, X. Henry Zhang, Paul Sajda, Punam K. Saha, Felix W. Wehrli, X. Edward Guo
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 375-376, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176408
https://doi.org/10.1115/SBC2007-176408
View Paper titled, Contributions of Trabecular Rods of Various Orientations in Determining the Elastic Properties of Human Vertebral Trabecular Bone
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Topics: Bone, Elasticity, Rods, Elastic moduli, Mechanical properties, Plates (structures), Computerized tomography, Diseases, Finite element analysis, Osteoporosis
Proceedings Papers

Calcium Signaling in Bone Cell Networks Induced by Fluid Flow

X. Lucas Lu, Bo Huo, Andrew D. Baik, X. Edward Guo
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 291-292, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206043
https://doi.org/10.1115/SBC2009-206043
View Paper titled, Calcium Signaling in Bone Cell Networks Induced by Fluid Flow
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Topics: Bone, Fluid dynamics, Osteoblasts, Junctions, Oscillations, Printing, Self-assembly
Proceedings Papers

A Semi-3D Real-Time Imaging Technique for Measuring Bone Cell Deformation Under Fluid Flow

Andrew D. Baik, X. Lucas Lu, Bo Huo, X. Sherry Liu, Cheng Dong, X. Edward Guo
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 823-824, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206524
https://doi.org/10.1115/SBC2009-206524
View Paper titled, A Semi-3D Real-Time Imaging Technique for Measuring Bone Cell Deformation Under Fluid Flow
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Topics: Bone, Deformation, Fluid dynamics, Imaging, Adhesion, Flow (Dynamics), Fluids, Microscopy, Osteoblasts, Shear (Mechanics)
Proceedings Papers

Individual Trabecula Segmentation (ITS)-Based Plate-Rod Microstructural Finite Element Model Predicts Nonlinear Mechanical Properties of Human Trabecular Bone

Bin Zhou, Ji Wang, Arnav Sanyal, Aaron J. Fields, Hong Wang, Tony M. Keaveny, Baohua Ji, X. Sherry Liu, X. Edward Guo
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 403-404, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80652
https://doi.org/10.1115/SBC2012-80652
View Paper titled, Individual Trabecula Segmentation (ITS)-Based Plate-Rod Microstructural Finite Element Model Predicts Nonlinear Mechanical Properties of Human Trabecular Bone
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Topics: Bone, Finite element model, Image segmentation, Mechanical properties, Resolution (Optics), Bricks, Computers, Diseases, Mechanical testing, Modeling
Proceedings Papers

Relationships Between Stiffness of Human Distal Tibia, Distal Radius, Proximal Femur, and Vertebral Body Assessed by HR-pQCT and cQCT Based Finite Element Analyses

X. Sherry Liu, Adi Cohen, Perry T. Yin, Joan M. Lappe, Robert R. Recker, Elizabeth Shane, X. Edward Guo
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 37-38, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-205457
https://doi.org/10.1115/SBC2009-205457
View Paper titled, Relationships Between Stiffness of Human Distal Tibia, Distal Radius, Proximal Femur, and Vertebral Body Assessed by HR-pQCT and cQCT Based Finite Element Analyses
Open the PDF for Relationships Between Stiffness of Human Distal Tibia, Distal Radius, Proximal Femur, and Vertebral Body Assessed by HR-pQCT and cQCT Based Finite Element Analyses in another window
Topics: Finite element analysis, Stiffness, Bone, Fracture (Materials), Fracture (Process), Stress, Computerized tomography, Lumbar spine, Mechanical properties, Risk
Proceedings Papers

µCT/HR-pQCT Image Based Plate-Rod Microstructural Finite Element Model Efficiently Predicts the Elastic Moduli and Yield Strength of Human Trabecular Bone

X. Sherry Liu, Aaron J. Fields, Tony M. Keaveny, Elizabeth Shane, X. Edward Guo
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 333-334, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19158
https://doi.org/10.1115/SBC2010-19158
View Paper titled, µCT/HR-pQCT Image Based Plate-Rod Microstructural Finite Element Model Efficiently Predicts the Elastic Moduli and Yield Strength of Human Trabecular Bone
Open the PDF for µCT/HR-pQCT Image Based Plate-Rod Microstructural Finite Element Model Efficiently Predicts the Elastic Moduli and Yield Strength of Human Trabecular Bone in another window
Topics: Bone, Elastic moduli, Finite element model, Yield strength, Resolution (Optics), Computation, Diseases, Failure, Finite element analysis, Fracture (Materials)
Proceedings Papers

Intercellular Calcium Wave Propagation in Linear and Circuit-Like Bone Cell Networks

X. Lucas Lu, Bo Huo, Andrew D. Baik, X. Edward Guo
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 335-336, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19365
https://doi.org/10.1115/SBC2010-19365
View Paper titled, Intercellular Calcium Wave Propagation in Linear and Circuit-Like Bone Cell Networks
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Topics: Bone, Circuits, Wave propagation, Chain, Diffusion (Physics), Junctions, Membranes, Transients (Dynamics), Waves
Proceedings Papers

Pseudo-3D Visualization of Cytoskeletal and Whole-Cell Deformation of MLO-Y4 Osteocytes Under Flow

Andrew D. Baik, X. Lucas Lu, Elizabeth M. Hillman, Cheng Dong, X. Edward Guo
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 351-352, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19239
https://doi.org/10.1115/SBC2010-19239
View Paper titled, Pseudo-3D Visualization of Cytoskeletal and Whole-Cell Deformation of MLO-Y4 Osteocytes Under Flow
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Topics: Deformation, Flow (Dynamics), Visualization, Fluids, Microscopy, Shear (Mechanics), Bone, Cell membranes, Resolution (Optics)