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Journal Articles

Biomechanical Response of Cancer Stem Cells to Low-Intensity Ultrasound

Yaozhang Yang, Meng Du, Jinsui Yu, Zhiyi Chen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2023, 145(9): 091001.
Paper No: BIO-21-1438
https://doi.org/10.1115/1.4062299
Published Online: May 22, 2023
View Article titled, Biomechanical Response of Cancer Stem Cells to Low-Intensity Ultrasound
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Topics: Cancer, Stem cells, Ultrasound, Drugs, Biomechanics, Stiffness
Journal Articles

Substrate Stiffness Modulates the Crosstalk Between Mesenchymal Stem Cells and Macrophages

Rukmani Sridharan, Daniel J. Kelly, Fergal J. O'Brien
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031001.
Paper No: BIO-18-1497
https://doi.org/10.1115/1.4048809
Published Online: December 10, 2020
View Article titled, Substrate Stiffness Modulates the Crosstalk Between Mesenchymal Stem Cells and Macrophages
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Topics: Stem cells, Stiffness
Journal Articles

Tuning Thermal Dosage to Facilitate Mesenchymal Stem Cell Osteogenesis in Pro-Inflammatory Environment

Kristifor Sunderic, Chenghai Li, A. H. Rezwanuddin Ahmed, Dionne Dawkins, Tala Azar, Luis Cardoso, Sihong Wang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2021, 143(1): 011006.
Paper No: BIO-20-1179
https://doi.org/10.1115/1.4047660
Published Online: September 29, 2020
View Article titled, Tuning Thermal Dosage to Facilitate Mesenchymal Stem Cell Osteogenesis in Pro-Inflammatory Environment
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Topics: DNA, Heat, Heating, Shock (Mechanics), Stem cells, Temperature, Minerals
Includes: Supplementary data
Journal Articles

Cholesterol-Dependent Modulation of Stem Cell Biomechanics: Application to Adipogenesis

Shan Sun, Djanybek Adyshev, Steven Dudek, Amit Paul, Andrew McColloch, Michael Cho
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2019, 141(8): 081005.
Paper No: BIO-18-1375
https://doi.org/10.1115/1.4043253
Published Online: May 6, 2019
View Article titled, Cholesterol-Dependent Modulation of Stem Cell Biomechanics: Application to Adipogenesis
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Topics: Atomic force microscopy, Biomechanics, Membranes, Proteins, Stem cells, Cellular mechanics, Stiffness, Elasticity
Journal Articles

Cellular Response to Cyclic Compression of Tissue Engineered Intervertebral Disk Constructs Composed of Electrospun Polycaprolactone

Andrea Fotticchia, Emrah Demirci, Cristina Lenardi, Yang Liu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2018, 140(6): 061002.
Paper No: BIO-17-1372
https://doi.org/10.1115/1.4039307
Published Online: March 16, 2018
View Article titled, Cellular Response to Cyclic Compression of Tissue Engineered Intervertebral Disk Constructs Composed of Electrospun Polycaprolactone
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Topics: Agar, Anisotropy, Biological tissues, Bioreactors, Bone, Compression, Compressive stress, Disks, Displacement, Electrospinning
Journal Articles

The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction

Spencer E. Szczesny, Robert L. Mauck
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2017, 139(2): 021006.
Paper No: BIO-16-1276
https://doi.org/10.1115/1.4035350
Published Online: January 19, 2017
View Article titled, The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction
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Topics: Fibers, Membranes, Proteins, Stiffness, Stress, Tension, Deformation, Cell membranes, Cellular mechanics, Stem cells
Journal Articles

Static and Cyclic Mechanical Loading of Mesenchymal Stem Cells on Elastomeric, Electrospun Polyurethane Meshes

Robyn D. Cardwell, Jonathan A. Kluge, Patrick S. Thayer, Scott A. Guelcher, Linda A. Dahlgren, David L. Kaplan, Aaron S. Goldstein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2015, 137(7): 071010.
Paper No: BIO-14-1238
https://doi.org/10.1115/1.4030404
Published Online: July 1, 2015
View Article titled, Static and Cyclic Mechanical Loading of Mesenchymal Stem Cells on Elastomeric, Electrospun Polyurethane Meshes
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Topics: Fibers, Stress, Urethane elastomers, Biological tissues, DNA, Imaging, Stem cells, Manganese (Metal), Biomaterials
Includes: Supplementary data
Journal Articles

Epigenetic Changes During Mechanically Induced Osteogenic Lineage Commitment

Julia C. Chen, Mardonn Chua, Raymond B. Bellon, Christopher R. Jacobs
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Forum
J Biomech Eng. February 2015, 137(2): 020902.
Paper No: BIO-14-1628
https://doi.org/10.1115/1.4029551
Published Online: February 1, 2015
View Article titled, Epigenetic Changes During Mechanically Induced Osteogenic Lineage Commitment
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Topics: DNA, Flow (Dynamics), Fluids, Shear stress, Stem cells, RNA, Chain
Journal Articles

Flexure-Based Device for Cyclic Strain-Mediated Osteogenic Differentiation

Kyung Shin Kang, Young Hun Jeong, Jung Min Hong, Woon-Jae Yong, Jong-Won Rhie, Dong-Woo Cho
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. November 2013, 135(11): 114501.
Paper No: BIO-12-1559
https://doi.org/10.1115/1.4025103
Published Online: September 23, 2013
View Article titled, Flexure-Based Device for Cyclic Strain-Mediated Osteogenic Differentiation
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Topics: Bending (Stress), Generators, Piezoelectric actuators, PLGA, Displacement, Design, Stem cells
Journal Articles

Elasticity of Human Embryonic Stem Cells as Determined by Atomic Force Microscopy

Robert Kiss, Henry Bock, Steve Pells, Elisabetta Canetta, Ashok K. Adya, Andrew J. Moore, Paul De Sousa, Nicholas A. Willoughby
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2011, 133(10): 101009.
https://doi.org/10.1115/1.4005286
Published Online: November 7, 2011
View Article titled, Elasticity of Human Embryonic Stem Cells as Determined by Atomic Force Microscopy
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Topics: Atomic force microscopy, Elasticity, Stem cells, Young's modulus, Fibroblasts
Journal Articles

Effect of Pulse Frequency on the Osteogenic Differentiation of Mesenchymal Stem Cells in a Pulsatile Perfusion Bioreactor

Katherine D. Kavlock, Aaron S. Goldstein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2011, 133(9): 091005.
https://doi.org/10.1115/1.4004919
Published Online: October 11, 2011
View Article titled, Effect of Pulse Frequency on the Osteogenic Differentiation of Mesenchymal Stem Cells in a Pulsatile Perfusion Bioreactor
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Topics: Bioreactors, Bone, Flow (Dynamics), Proteins, Pulsatile flow, Stem cells, PLGA
Journal Articles

Hydrostatic Pressure Stimulation of Human Mesenchymal Stem Cells Seeded on Collagen-Based Artificial Extracellular Matrices

Ricarda Hess, Timothy Douglas, Kenneth A. Myers, Barbe Rentsch, Claudia Rentsch, Hartmut Worch, Nigel G. Shrive, David A. Hart, Dieter Scharnweber
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2010, 132(2): 021001.
https://doi.org/10.1115/1.4000194
Published Online: December 28, 2009
View Article titled, Hydrostatic Pressure Stimulation of Human Mesenchymal Stem Cells Seeded on Collagen-Based Artificial Extracellular Matrices
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Topics: Bone, Hydrostatic pressure, Proteins, Stem cells, Coatings, Polishing equipment
Journal Articles

Mechanical Characterization of Differentiated Human Embryonic Stem Cells

Gidon Ofek, Vincent P. Willard, Eugene J. Koay, Jerry C. Hu, Patrick Lin, Kyriacos A. Athanasiou
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. June 2009, 131(6): 061011.
https://doi.org/10.1115/1.3127262
Published Online: May 8, 2009
View Article titled, Mechanical Characterization of Differentiated Human Embryonic Stem Cells
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Topics: Biomechanics, Cartilage, Cellular mechanics, Chondrocytes, Creep, Density, Mechanical properties, Separation (Technology), Stem cells, Tissue engineering
Journal Articles

Development and Validation of a System for the Growth of Cells and Tissues Under Intermittent Hydrostatic Pressure

Troy J. Eggum, Christopher J. Hunter
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. December 2008, 130(6): 064501.
https://doi.org/10.1115/1.2979864
Published Online: October 10, 2008
View Article titled, Development and Validation of a System for the Growth of Cells and Tissues Under Intermittent Hydrostatic Pressure
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Topics: Biological tissues, Bioreactors, Design, Glucose, Hydrostatic pressure, Oxygen, Pressure, Stem cells, Pressure testing, Intervertebral discs
Journal Articles

Mechanisms of Strain-Mediated Mesenchymal Stem Cell Apoptosis

E. M. Kearney, P. J. Prendergast, V. A. Campbell
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. December 2008, 130(6): 061004.
https://doi.org/10.1115/1.2979870
Published Online: October 9, 2008
View Article titled, Mechanisms of Strain-Mediated Mesenchymal Stem Cell Apoptosis
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Topics: DNA, Proteins, Signals, Stem cells, Stress, Tissue engineering, Gadolinium, Fluorescence, Biological tissues
Journal Articles

Mechanical Stimulation of Tissue Engineered Tendon Constructs: Effect of Scaffold Materials

Victor S. Nirmalanandhan, Ph.D., Matthew R. Dressler, Ph.D., Jason T. Shearn, Ph.D., Natalia Juncosa-Melvin, Ph.D., Marepalli Rao, Ph.D., Cynthia Gooch, BS, LVT, Gino Bradica, Ph.D., David L. Butler, Ph.D.
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. December 2007, 129(6): 919–923.
https://doi.org/10.1115/1.2800828
Published Online: April 24, 2007
View Article titled, Mechanical Stimulation of Tissue Engineered Tendon Constructs: Effect of Scaffold Materials
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Topics: Biological tissues, Biomechanics, Silicones, Stem cells, Stiffness, Tendons, Maintenance, Mechanical properties, Tissue engineering
Journal Articles

A New Experimental System for the Extended Application of Cyclic Hydrostatic Pressure to Cell Culture

Timothy M. Maul, B.S., Douglas W. Hamilton, Ph.D., Alejandro Nieponice, M.D., Lorenzo Soletti, M.S.E., David A. Vorp, Ph.D.
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2007, 129(1): 110–116.
https://doi.org/10.1115/1.2401190
Published Online: June 23, 2006
View Article titled, A New Experimental System for the Extended Application of Cyclic Hydrostatic Pressure to Cell Culture
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Topics: Computational fluid dynamics, Hydrostatic pressure, Pressure, Design, Stem cells, Shear stress, Bone, Flow (Dynamics)
Journal Articles

A 3D Computational Simulation of Fracture Callus Formation: Influence of the Stiffness of the External Fixator

M. J. Gómez-Benito, J. M. García-Aznar, J. H. Kuiper, M. Doblaré
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. June 2006, 128(3): 290–299.
https://doi.org/10.1115/1.2187045
Published Online: November 9, 2005
View Article titled, A 3D Computational Simulation of Fracture Callus Formation: Influence of the Stiffness of the External Fixator
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Topics: Biological tissues, Fracture (Materials), Fracture (Process), Stiffness, Bone, Simulation, Stress, Finite element analysis, Stem cells
Journal Articles

Cellular Response of Adipose Derived Passage-4 Adult Stem Cells to Freezing Stress

Ram V. Devireddy, Sreedhar Thirumala, Jeffrey M. Gimble
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. December 2005, 127(7): 1081–1086.
https://doi.org/10.1115/1.2073673
Published Online: July 13, 2005
View Article titled, Cellular Response of Adipose Derived Passage-4 Adult Stem Cells to Freezing Stress
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Topics: Cooling, Freezing, Membranes, Permeability, Stem cells, Water, Shrinkage (Materials), Stress