We derive a cellular solids approach to the design of bone scaffolds for stiffness and pore size. Specifically, we focus on scaffolds made of stacked, alternating, orthogonal layers of hydroxyapatite rods, such as those obtained via micro-robotic deposition, and aim to determine the rod diameter, spacing and overlap required to obtain specified elastic moduli and pore size. To validate and calibrate the cellular solids model, we employ a finite element model and determine the effective scaffold moduli via numerical homogenization. In order to perform an efficient, automated execution of the numerical studies, we employ a geometry projection method so that analyses corresponding to different scaffold dimensions can be performed on a fixed, non-conforming mesh. Based on the developed model, we provide design charts to aid in the selection of rod diameter, spacing and overlap to be used in the robotic deposition to attain desired elastic moduli and pore size.
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e-mail: ajwj@illinois.edu
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September 2011
Research Papers
A Computational and Cellular Solids Approach to the Stiffness-Based Design of Bone Scaffolds
J.A. Norato,
J.A. Norato
Visiting Research Assistant Professor
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A. J. Wagoner Johnson
A. J. Wagoner Johnson
Assistant Professor
Department of Mechanical Science and Engineering,
e-mail: ajwj@illinois.edu
University of Illinois at Urbana-Champaign
, Urbana, IL 61801
Search for other works by this author on:
J.A. Norato
Visiting Research Assistant Professor
A. J. Wagoner Johnson
Assistant Professor
Department of Mechanical Science and Engineering,
University of Illinois at Urbana-Champaign
, Urbana, IL 61801e-mail: ajwj@illinois.edu
J Biomech Eng. Sep 2011, 133(9): 091003 (8 pages)
Published Online: October 4, 2011
Article history
Received:
February 9, 2011
Accepted:
September 5, 2011
Online:
October 4, 2011
Published:
October 4, 2011
Citation
Norato, J., and Wagoner Johnson, A. J. (October 4, 2011). "A Computational and Cellular Solids Approach to the Stiffness-Based Design of Bone Scaffolds." ASME. J Biomech Eng. September 2011; 133(9): 091003. https://doi.org/10.1115/1.4004994
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