Sustained tissue compression can lead to pressure ulcers, which can either start superficially or within deeper tissue layers. The latter type includes deep tissue injury, starting in skeletal muscle underneath an intact skin. Since the underlying damage mechanisms are poorly understood, prevention and early detection are difficult. Recent in vitro studies and in vivo animal studies have suggested that tissue deformation per se can lead to damage. In order to conclusively couple damage to deformation, experiments are required in which internal tissue deformation and damage are both known. Magnetic resonance (MR) tagging and T2-weighted MR imaging can be used to measure tissue deformation and damage, respectively, but they cannot be combined in a protocol for measuring damage after prolonged loading. Therefore, a dedicated finite element model was developed to calculate strains in damage experiments. In the present study, this model, which describes the compression of rat skeletal muscles, was validated with MR tagging. Displacements from both the tagging experiments and the model were interpolated on a grid and subsequently processed to obtain maximum shear strains. A correlation analysis revealed a linear correlation between experimental and numerical strains. It was further found that the accuracy of the numerical prediction decreased for increasing strains, but the positive predictive value remained reasonable. It was concluded that the model was suitable for calculating strains in skeletal muscle tissues in which damage is measured due to compression.
Skip Nav Destination
e-mail: k.k.ceelen@tue.nl
Article navigation
December 2008
Research Papers
Validation of a Numerical Model of Skeletal Muscle Compression With MR Tagging: A Contribution to Pressure Ulcer Research
K. K. Ceelen,
K. K. Ceelen
Department of Biomedical Engineering,
e-mail: k.k.ceelen@tue.nl
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
A. Stekelenburg,
A. Stekelenburg
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
J. L. J. Mulders,
J. L. J. Mulders
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
G. J. Strijkers,
G. J. Strijkers
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
F. P. T. Baaijens,
F. P. T. Baaijens
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
K. Nicolay,
K. Nicolay
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
C. W. J. Oomens
C. W. J. Oomens
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
K. K. Ceelen
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlandse-mail: k.k.ceelen@tue.nl
A. Stekelenburg
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
J. L. J. Mulders
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
G. J. Strijkers
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
F. P. T. Baaijens
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
K. Nicolay
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
C. W. J. Oomens
Department of Biomedical Engineering,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The NetherlandsJ Biomech Eng. Dec 2008, 130(6): 061015 (8 pages)
Published Online: October 23, 2008
Article history
Received:
November 15, 2007
Revised:
July 21, 2008
Published:
October 23, 2008
Citation
Ceelen, K. K., Stekelenburg, A., Mulders, J. L. J., Strijkers, G. J., Baaijens, F. P. T., Nicolay, K., and Oomens, C. W. J. (October 23, 2008). "Validation of a Numerical Model of Skeletal Muscle Compression With MR Tagging: A Contribution to Pressure Ulcer Research." ASME. J Biomech Eng. December 2008; 130(6): 061015. https://doi.org/10.1115/1.2987877
Download citation file:
Get Email Alerts
Related Articles
Computer Simulation of Female Urinary Incontinence
J. Med. Devices (June,2008)
Adaptive Surrogate Modeling for Efficient Coupling of Musculoskeletal Control and Tissue Deformation Models
J Biomech Eng (January,2009)
Development and Validation of a Three-Dimensional Finite Element Model of the Face
J Biomech Eng (April,2009)
Related Proceedings Papers
Related Chapters
Clinical issues and experience
Mechanical Blood Trauma in Circulatory-Assist Devices
Data Tabulations
Structural Shear Joints: Analyses, Properties and Design for Repeat Loading
Introduction
Mechanical Blood Trauma in Circulatory-Assist Devices